Biotechnology: Bridging Research and Applications: by Ruth Arnon (auth.), Dr. Daphne Kamely, Dr. Ananda M.

By Ruth Arnon (auth.), Dr. Daphne Kamely, Dr. Ananda M. Chakrabarty, Dr. Steven E. Kornguth (eds.)

Biotechnology is advancing at a swift velocity with various purposes in medication, undefined, agriculture and environmental remediation. spotting this, govt, commercial and educational study and improvement make investments­ ment in biotechnology has elevated speedily. The prior decade has obvious the emergence of purposes of this expertise with a dual-use power. Mili­ tary functions specialize in 4 significant components: biomedical know-how, corresponding to vaccine improvement and scientific diagnostics; detection of poisons, chemical substances and pathogens; fabric biotechnology; and organic decontamination, in­ cluding biodegradation and bioremediation. This convention emphasizes the non-medical functions of biotechnol­ ogy. the 1st periods specialize in the synthesis and houses of molecules which may be utilized in detectors. the normal method of detection of chemical and organic brokers trusted the improvement of particular assays or analyses for identified brokers. Advances in molecular biology have made attainable the creation of enormous amounts of poisons that have been formerly to be had in minute amounts, and the molecular engineering of poisons and pathogens with particular pharmacologic and physical-chemical houses. as well as the normal techniques to detection of particular identified compounds, biotechnology now bargains well-known techniques to detection. Physiological goals, referred to as receptors, are basic objectives for lots of medications and pollutants. equally, pathogens depend upon receptors to realize entry to cells. those receptors functionality as delicate detectors, producing signs that are transduced and amplified.

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Extra resources for Biotechnology: Bridging Research and Applications: Proceedings of the U.S.-Israel Research Conference on Advances in Applied Biotechnology June 24–30, 1990; Haifa, Israel

Example text

For some areas of the world, oxygenated fuels). ): processes that produce commodity or speciality chemicals especially compared with today's chemical processing of vegetable materials appear to be economical. Scaling up bioreactors and fermentors, using numerically controlled systems to modulate conditions in the fermentation stream are being accomplished as process engineers are brought to the biologist'S bench. Manufacturing and Biotechnology Synergisms 35 o Innovation: an incredibly large number of possibly valuable products are being defined by biological methods that appear to now be possible with what will become routine genetic manipulation in the next two decades.

Arranged in terms of level of spending required or level of commitment versus the method of entry, there is a wide range of either dollars required or intellectual activity needed within a corporation to be successful (Figure 15). In the case of stock purchase and acquisition, considerable differences exist because of the time required for legal costs and personal involvement. Without quite understanding why, this is probably the reason that corporations are becoming more involved in direct acquisitions after products appear from start-up companies as opposed to early participation.

What do we want from biotechnology in medium industry? Not surprisingly there are only three possibilities: a product, a process to sell, or a process to use from which we can gain a competitive advantage. Why are we interested now in biotechnology, when the "hit-rate" from ventures is so low, the returns on investment are almost non-existent, a few percent of all initiatives succeed, and tax incentives are missing? , for some areas of the world, oxygenated fuels). ): processes that produce commodity or speciality chemicals especially compared with today's chemical processing of vegetable materials appear to be economical.

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